Nanotechnology in Thoracic Surgery

David A. Mahvi, MD, Mark W. Grinstaff, PhD, Yolonda L. Colson, MD, PhD

Key Elements

  • An array of nanotherapeutic delivery platforms are currently being investigated to provide novel therapeutic options for thoracic malignancies
  • Multiple chemotherapeutic drugs and/or gene delivery via nanotechnology platforms demonstrate efficacy in pre-clinical and limited clinical studies
  • New polymer formulations that improve biocompatibility and tumor targeting with stimuli-responsiveness are maximizing therapeutic efficacy and minimizing adverse effects
  • Nanotheranostics is a new field combining diagnostic and therapeutic modalities that will expedite next-generation, personalized medicine

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Last updated: October 18, 2022