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Tracheal Replacement Strategies

Pierre Delaere, MD, PhD, Tony Lerut, MD, FRCS, Dirk Van Raemdonck, MD, PhD, Louise De Prins
Tracheal Replacement Strategies is a topic covered in the Pearson's General Thoracic.

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Keypoints

  • Tracheal regeneration is as unlikely as the regeneration of an external ear or nose.
  • Orthotopic revascularization of the trachea is only currently possible with autotransplants.
  • Orthotopic tracheal patch transplantation is possible after heterotopic revascularization.
  • Immunosuppressive drugs are necessary for tracheal allograft revascularization.
  • Chondrocytes are immunologically privileged because they are protected within a matrix.
  • There are not yet any reliable reconstruction techniques for long, circumferential tracheal defects.

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Keypoints

  • Tracheal regeneration is as unlikely as the regeneration of an external ear or nose.
  • Orthotopic revascularization of the trachea is only currently possible with autotransplants.
  • Orthotopic tracheal patch transplantation is possible after heterotopic revascularization.
  • Immunosuppressive drugs are necessary for tracheal allograft revascularization.
  • Chondrocytes are immunologically privileged because they are protected within a matrix.
  • There are not yet any reliable reconstruction techniques for long, circumferential tracheal defects.

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Last updated: October 26, 2022