Mediastinal Parathyroid Tumors
- Understanding the embryologic origins of the superior and inferior parathyroids helps guide exploration, particularly when seeking undiscovered or ectopic glands.
- Mediastinal parathyroids can be found in 11% to 22% of patients, but only 2% to 4% require sternotomy for removal. Most can be removed via a cervical approach.
- Imaging studies are indicated for any question of mediastinal or intrathoracic parathyroids:99mTc-sestamibi and new 4-D computed tomography (CT) are most commonly employed.
- Intraoperative parathyroid hormone monitoring is now a critical adjunct in the surgical treatment of parathyroid disease and can limit the extent of surgery.
- Never discard normal parathyroid tissue, and always treat any parathyroid tissue discovered during reoperations as the patient’s only remaining tissue.
- Hyperparathyroidism, considering all cases, is cured by surgery 95% to 99% of the time, including 90% of reoperations and 95% of reoperations with successful localization.
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Last updated: January 5, 2021
Hall, Bruce L, et al. "Mediastinal Parathyroid Tumors." Pearson's General Thoracic Surgery. STS Cardiothoracic Surgery E-Book, Chicago: Society of Thoracic Surgeons, 2021. STS Surgery, ebook.sts.org.
Hall BL, Moley J, Norton J. Mediastinal Parathyroid Tumors. In: Darling GE, Baumgartner WA, Jacobs JP, eds. Pearson's General Thoracic Surgery. STS Cardiothoracic Surgery E-Book. Chicago: Society of Thoracic Surgeons; 2021. ebook.sts.org. Accessed September 23, 2023.
Hall, B. L., Moley, J., & Norton, J. (2021). Mediastinal Parathyroid Tumors. In Darling, G., Baumgartner, W., & Jacobs, J. (Eds.), Pearson's General Thoracic Surgery. STS Cardiothoracic Surgery E-Book. Chicago: Society of Thoracic Surgeons. ebook.sts.org
Hall BL, Moley J, Norton J. Mediastinal Parathyroid Tumors [Internet]. In: Darling GE, Baumgartner WA, Jacobs JP, editors. Pearson's General Thoracic Surgery. STS Cardiothoracic Surgery E-Book. Chicago: Society of Thoracic Surgeons; 2021. [cited 2023 September 23]. Available from: ebook.sts.org.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Mediastinal Parathyroid Tumors ID - 1418506 ED - Jacobs,J, ED - Darling,Gail, ED - Baumgartner,William, Y1 - 2021/01/05/ BT - Pearson's General Thoracic UR - https://ebook.sts.org/sts/view/Pearsons-General-Thoracic/1418506/all/Mediastinal_Parathyroid_Tumors PB - Chicago: Society of Thoracic Surgeons DB - STS Surgery DP - Unbound Medicine ER -