Induction and Adjuvant Therapy for Operable Non-Small Cell Lung Cancer
Induction and Adjuvant Therapy for Operable Non-Small Cell Lung Cancer is a topic covered in the Pearson's General Thoracic.
To view the entire topic, please log in or purchase a subscription.
STS Cardiothoracic Surgery E-Book from The Society of Thoracic Surgeons provides expert guidance for Cardiac and Thoracic Surgery. Sections include Pearson’s General Thoracic, Esphageal, Adult Cardiac, and Pediatric and Congenital Cardiac Surgery. Explore these free sample topics:
-- The first section of this topic is shown below --
Key Points
- Chemotherapy given prior to surgery has been shown to improve survival in both early-stage and locally advanced non-small-cell lung cancer (NSCLC), although typically induction chemotherapy is recommended for only locally advanced NSCLC
- There are no significant differences in survival between patients undergoing induction chemotherapy and induction chemoradiation for N2 NSCLC
- Chemotherapy given after surgery for N1 and N2 NSCLC has been shown to improve survival. Adjuvant chemotherapy should also be considered for patients with stage IB disease with high-risk factorsT
- Adjuvant radiation is not currently recommended for early-stage NSCLC that has been completely resected. Adjuvant radiation may be considered in select cases of stage IIIA after discussion in a multidisciplinary setting. Radiation can be considered after surgery for R1 and R2 resection
- Several new randomized trials are evaluating the efficacy of molecularly targeted agents and immunotherapy in the induction and adjuvant setting
-- To view the remaining sections of this topic, please log in or purchase a subscription --
Key Points
- Chemotherapy given prior to surgery has been shown to improve survival in both early-stage and locally advanced non-small-cell lung cancer (NSCLC), although typically induction chemotherapy is recommended for only locally advanced NSCLC
- There are no significant differences in survival between patients undergoing induction chemotherapy and induction chemoradiation for N2 NSCLC
- Chemotherapy given after surgery for N1 and N2 NSCLC has been shown to improve survival. Adjuvant chemotherapy should also be considered for patients with stage IB disease with high-risk factorsT
- Adjuvant radiation is not currently recommended for early-stage NSCLC that has been completely resected. Adjuvant radiation may be considered in select cases of stage IIIA after discussion in a multidisciplinary setting. Radiation can be considered after surgery for R1 and R2 resection
- Several new randomized trials are evaluating the efficacy of molecularly targeted agents and immunotherapy in the induction and adjuvant setting
There's more to see -- the rest of this topic is available only to subscribers.
Last updated: January 3, 2020
Citation
Yang, Chi-Fu J, et al. "Induction and Adjuvant Therapy for Operable Non-Small Cell Lung Cancer." Pearson's General Thoracic Surgery. STS Cardiothoracic Surgery E-Book, Chicago: Society of Thoracic Surgeons, 2020. STS Surgery, ebook.sts.org.
Yang CJ, Shah S, D’Amico T. Induction and Adjuvant Therapy for Operable Non-Small Cell Lung Cancer. In: Darling GE, Baumgartner WA, Jacobs JP, eds. Pearson's General Thoracic Surgery. STS Cardiothoracic Surgery E-Book. Chicago: Society of Thoracic Surgeons; 2020. ebook.sts.org. Accessed March 24, 2023.
Yang, C. J., Shah, S., & D’Amico, T. (2020). Induction and Adjuvant Therapy for Operable Non-Small Cell Lung Cancer. In Darling, G., Baumgartner, W., & Jacobs, J. (Eds.), Pearson's General Thoracic Surgery. STS Cardiothoracic Surgery E-Book. Chicago: Society of Thoracic Surgeons. ebook.sts.org
Yang CJ, Shah S, D’Amico T. Induction and Adjuvant Therapy for Operable Non-Small Cell Lung Cancer [Internet]. In: Darling GE, Baumgartner WA, Jacobs JP, editors. Pearson's General Thoracic Surgery. STS Cardiothoracic Surgery E-Book. Chicago: Society of Thoracic Surgeons; 2020. [cited 2023 March 24]. Available from: ebook.sts.org.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Induction and Adjuvant Therapy for Operable Non-Small Cell Lung Cancer
ID - 1418467
ED - Jacobs,J,
ED - Darling,Gail,
ED - Baumgartner,William,
Y1 - 2020/01/03/
BT - Pearson's General Thoracic
UR - https://ebook.sts.org/sts/view/Pearsons-General-Thoracic/1418467/all/Induction_and_Adjuvant_Therapy_for_Operable_Non_Small_Cell_Lung_Cancer
PB - Chicago: Society of Thoracic Surgeons
DB - STS Surgery
DP - Unbound Medicine
ER -