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Screening and Early Detection of Lung Cancer

DuyKhanh P. Ceppa, MD, Vignesh Raman, MD, MHS, Tina D. Tailor, MD, Betty C. Tong, MD, MS, MHS
Screening and Early Detection of Lung Cancer is a topic covered in the Pearson's General Thoracic.

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Key Points

  • Historical studies of lung cancer screening utilized plain chest radiography (CXR) and sputum analysis, neither of which were effective in reducing lung cancer mortality.
  • Contemporary studies of lung cancer screening with low-dose computed tomography (LDCT) have demonstrated significant reduction in lung cancer mortality.
  • There are sex-based differences in mortality reduction when using LDCT lung cancer screening.
  • Barriers exist in recruitment and retention of patients qualified for LDCT lung cancer screening.
  • Adjuncts to radiographic screening, including biomarkers and radiomic analysis of screen-detected lesions, are currently being studied.

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Key Points

  • Historical studies of lung cancer screening utilized plain chest radiography (CXR) and sputum analysis, neither of which were effective in reducing lung cancer mortality.
  • Contemporary studies of lung cancer screening with low-dose computed tomography (LDCT) have demonstrated significant reduction in lung cancer mortality.
  • There are sex-based differences in mortality reduction when using LDCT lung cancer screening.
  • Barriers exist in recruitment and retention of patients qualified for LDCT lung cancer screening.
  • Adjuncts to radiographic screening, including biomarkers and radiomic analysis of screen-detected lesions, are currently being studied.

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Last updated: August 24, 2020